The most effective treatment to date for somatization disorder

Somatic symptom disorders may present to the emergency room for assessment and treatment during periods of acute increase in symptom severity.

Electroconvulsive therapy is not effective for somatic symptom disorders, but it may successfully treat somatic symptoms related to an underlying mood disorder.

Obtain necessary studies to rule out physical causes such as myocardial infarction or appendicitis.

Intravenous or oral acute sedation with benzodiazepines may be used. Avoid long-term benzodiazepines for somatic symptom disorders. Avoid acute or long-term narcotic analgesics for somatic symptom disorders.

Primary care management

Randomized trials have demonstrated the value of physician education in the management of the patient with somatization. [20, 21] Cognitive-behavioral psychotherapy strategies may be specifically helpful in reducing distress and high medical use. Psychosocial interventions directed by physicians form the basis for successful treatment. A strong relationship between the patient and the primary care physician can assist in long-term management.

Psychoeducation can be helpful by letting the patient know that physical symptoms may be exacerbated by anxiety or other emotional problems. However, be careful because patients are likely to resist suggestions that their condition is due to emotional rather than physical problems.

The primary care physician should inform the patient that the symptoms do not appear to be due to a life-threatening, disabling, medical condition and should schedule regular visits for reassessment and reinforcement of the lacking severity of ongoing symptoms.

The patient also may be told that some patients with similar symptoms have had spontaneous improvement, implying that spontaneous improvement may occur. However, the physician should accept the patient's physical symptoms and not pursue a goal of symptom resolution.

Indeed, regular, noninvasive, medical assessment reduces anxiety and limits health care–seeking behavior; this may be facilitated by regularly scheduled visits with the patient's primary care physician.

Encourage patients to remain active and limit the effect of target symptoms on the quality of life and daily functioning.

Family members should not become preoccupied with the patients physical symptoms or medical care. Family members should direct the patient to report symptoms to their primary care physician.

Regular exercise has been demonstrated to reduce functional somatic syndromes in some patients. [22]

Psychosocial interventions

Patients may resist suggestions for individual or group psychotherapy because they view their illness as a medical problem. Patients who accept psychotherapy may be able to reduce health care utilization. Psychosocial interventions that focus on maintaining social and occupational function despite chronic medical symptoms may be helpful. Somatic symptom disorders have been linked to impairments in emotion processing, which may contribute to the development of medically unexplained physical complaints. This may make emotion processing an important target for psychotherapeutic approaches to the treatment of somatic symptom disorders. [23]

Studies have shown that cognitive-behavioral therapy [24] reduces depressive symptoms in people with somatic diseases. In particular, this type of therapy is especially effective for patients who fit the criteria for a depressive disorder. Cognitive-behavioral therapy was superior to control conditions, with even greater effects to groups restricted to participants with depressive disorder. [25]

The most effective treatment to date for somatization disorder

Medication

 

 

References

  1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington, VA: American Psychiatric Publishing; 2013.

  2. Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Association. Fourth Edition. Washington, DC: American Psychiatric Association; 2000. Text Revision.

  3. Holliday KL, Macfarlane GJ, Nicholl BI, Creed F, Thomson W, McBeth J. Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. J Psychosom Res. 2010 May. 68 (5):469-74. [QxMD MEDLINE Link].

  4. Atmaca M, Sirlier B, Yildirim H, Kayali A. Hippocampus and amygdalar volumes in patients with somatization disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15. 35(7):1699-703. [QxMD MEDLINE Link].

  5. van der Kruijs SJ, Bodde NM, Vaessen MJ, Lazeron RH, Vonck K, Boon P, et al. Functional connectivity of dissociation in patients with psychogenic non-epileptic seizures. J Neurol Neurosurg Psychiatry. 2012 Mar. 83(3):239-47. [QxMD MEDLINE Link].

  6. Kurlansik SL, Maffei MS. Somatic Symptom Disorder. Am Fam Physician. 2016 Jan 1. 93 (1):49-54. [QxMD MEDLINE Link].

  7. Hilderink PH, Collard R, Rosmalen JG, Oude Voshaar RC. Prevalence of somatoform disorders and medically unexplained symptoms in old age populations in comparison with younger age groups: a systematic review. Ageing Res Rev. 2013 Jan. 12 (1):151-6. [QxMD MEDLINE Link].

  8. Limburg K, Sattel H, Radziej K, Lahmann C. DSM-5 somatic symptom disorder in patients with vertigo and dizziness symptoms. J Psychosom Res. 2016 Dec. 91:26-32. [QxMD MEDLINE Link].

  9. Baruffol E, Thilmany MC. Anxiety, depression, somatization and alcohol abuse. Prevalence rates in a general Belgian community sample. Acta Psychiatr Belg. 1993 May-Jun. 93(3):136-53. [QxMD MEDLINE Link].

  10. Chioqueta AP, Stiles TC. Suicide risk in patients with somatization disorder. Crisis. 2004. 25(1):3-7. [QxMD MEDLINE Link].

  11. Wiborg JF, Gieseler D, Fabisch AB, Voigt K, Lautenbach A, Löwe B. Suicidality in primary care patients with somatoform disorders. Psychosom Med. 2013 Nov-Dec. 75 (9):800-6. [QxMD MEDLINE Link].

  12. Okland TS, Gonzalez JR, Ferber AT, Mann SE. Association Between Patient Review of Systems Score and Somatization. JAMA Otolaryngol Head Neck Surg. 2017 Sep 1. 143 (9):870-875. [QxMD MEDLINE Link].

  13. Kendler KS, Aggen SH, Knudsen GP, Røysamb E, Neale MC, Reichborn-Kjennerud T. The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders. Am J Psychiatry. 2011 Jan. 168(1):29-39. [QxMD MEDLINE Link]. [Full Text].

  14. Maes M, Galecki P, Verkerk R, Rief W. Somatization, but not depression, is characterized by disorders in the tryptophan catabolite (TRYCAT) pathway, indicating increased indoleamine 2,3-dioxygenase and lowered kynurenine aminotransferase activity. Neuro Endocrinol Lett. 2011. 32(3):264-73. [QxMD MEDLINE Link].

  15. Katzer A, Oberfeld D, Hiller W, Gerlach AL, Witthöft M. Tactile perceptual processes and their relationship to somatoform disorders. J Abnorm Psychol. 2012 May. 121(2):530-43. [QxMD MEDLINE Link].

  16. Gao X, McSwiney P, Court A, Wiggins A, Sawyer SM. Somatic Symptom Disorders in Adolescent Inpatients. J Adolesc Health. 2018 Dec. 63 (6):779-784. [QxMD MEDLINE Link].

  17. Laferton JAC, Stenzel NM, Rief W, Klaus K, Brähler E, Mewes R. Screening for DSM-5 Somatic Symptom Disorder: Diagnostic Accuracy of Self-Report Measures Within a Population Sample. Psychosom Med. 2017 Nov/Dec. 79 (9):974-981. [QxMD MEDLINE Link].

  18. Gierk B, Kohlmann S, Kroenke K, Spangenberg L, Zenger M, Brähler E, et al. The somatic symptom scale-8 (SSS-8): a brief measure of somatic symptom burden. JAMA Intern Med. 2014 Mar. 174 (3):399-407. [QxMD MEDLINE Link].

  19. Werring DJ, Weston L, Bullmore ET. Functional magnetic resonance imaging of the cerebral response to visual stimulation in medically unexplained visual loss. Psychol Med. 2004 May. 34(4):583-9. [QxMD MEDLINE Link].

  20. Martin A, Rauh E, Fichter M, Rief W. A one-session treatment for patients suffering from medically unexplained symptoms in primary care: a randomized clinical trial. Psychosomatics. 2007 Jul-Aug. 48(4):294-303. [QxMD MEDLINE Link].

  21. Smith GR Jr, Monson RA, Ray DC. Psychiatric consultation in somatization disorder. A randomized controlled study. N Engl J Med. 1986 May 29. 314(22):1407-13. [QxMD MEDLINE Link].

  22. Hennings A, Schwarz MJ, Riemer S, Stapf TM, Selberdinger VB, Rief W. Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA. Psychiatry Res. 2013 Dec 30. 210 (3):925-33. [QxMD MEDLINE Link].

  23. Erkic M, Bailer J, Fenske SC, Schmidt SNL, Trojan J, Schröder A, et al. Impaired emotion processing and a reduction in trust in patients with somatic symptom disorder. Clin Psychol Psychother. 2018 Jan. 25 (1):163-172. [QxMD MEDLINE Link].

  24. Bleichhardt G, Timmer B, Rief W. Cognitive-behavioural therapy for patients with multiple somatoform symptoms--a randomised controlled trial in tertiary care. J Psychosom Res. 2004 Apr. 56(4):449-54. [QxMD MEDLINE Link].

  25. Beltman MW, Voshaar RC, Speckens AE. Cognitive-behavioural therapy for depression in people with a somatic disease: meta-analysis of randomised controlled trials. Br J Psychiatry. 2010 Jul. 197(1):11-9. [QxMD MEDLINE Link].

  26. Huang M, Luo B, Hu J, Wei N, Chen L, Wang S, et al. Combination of citalopram plus paliperidone is better than citalopram alone in the treatment of somatoform disorder: results of a 6-week randomized study. Int Clin Psychopharmacol. 2012 May. 27(3):151-8. [QxMD MEDLINE Link].

  27. Barsky AJ, Ahern DK. Cognitive behavior therapy for hypochondriasis: a randomized controlled trial. JAMA. 2004 Mar 24. 291(12):1464-70. [QxMD MEDLINE Link].

  28. Egloff N, Cámara RJ, von Känel R, Klingler N, Marti E, Ferrari ML. Hypersensitivity and hyperalgesia in somatoform pain disorders. Gen Hosp Psychiatry. 2014 May-Jun. 36(3):284-90. [QxMD MEDLINE Link].

  29. Harris AM, Orav EJ, Bates DW, Barsky AJ. Somatization increases disability independent of comorbidity. J Gen Intern Med. 2009 Feb. 24(2):155-61. [QxMD MEDLINE Link]. [Full Text].

  30. Kroenke K. Efficacy of treatment for somatoform disorders: a review of randomized controlled trials. Psychosom Med. 2007 Dec. 69(9):881-8. [QxMD MEDLINE Link].

  31. Olesen J, Gustavsson A, Svensson M, Wittchen HU, Jönsson B. The economic cost of brain disorders in Europe. Eur J Neurol. 2012 Jan. 19(1):155-62. [QxMD MEDLINE Link].

  32. Roca M, Gili M, Garcia-Garcia M, Salva J, Vives M, Garcia Campayo J, et al. Prevalence and comorbidity of common mental disorders in primary care. J Affect Disord. 2009 Apr 9. [QxMD MEDLINE Link].

  33. Sumathipala A, Siribaddana S, Abeysingha MR, De Silva P, Dewey M, Prince M, et al. Cognitive-behavioural therapy v. structured care for medically unexplained symptoms: randomised controlled trial. Br J Psychiatry. 2008 Jul. 193(1):51-9. [QxMD MEDLINE Link].

  34. van Ravesteijn H, Wittkampf K, Lucassen P, van de Lisdonk E, van den Hoogen H, van Weert H, et al. Detecting somatoform disorders in primary care with the PHQ-15. Ann Fam Med. 2009 May-Jun. 7(3):232-8. [QxMD MEDLINE Link].

  35. Kleinstäuber M, Witthöft M, Steffanowski A, van Marwijk H, Hiller W, Lambert MJ. Pharmacological interventions for somatoform disorders in adults. Cochrane Database Syst Rev. 2014 Nov 7. CD010628. [QxMD MEDLINE Link].

    What is the most effective treatment for somatization disorder?

    Psychotherapy. Because physical symptoms can be related to psychological distress and a high level of health anxiety, psychotherapy — specifically, cognitive behavioral therapy (CBT) — can help improve physical symptoms.

    What medication is used for somatization disorder?

    Medication: Common Prescription Drugs for Somatic Symptom Disorder.
    Imipramine (Tofranil)*.
    Fluoxetine (Prozac)*.
    Sertraline (Zoloft)*.
    Citalopram (Celexa)*.
    Escitalopram (Lexapro)*.
    Fluvoxamine (Luvox CR)*.
    Paroxetine (Pexeva, Paxil, Paxil CR)*.
    Mirtazapine (Remeron, Remeron SolTab)*.

    What is the best antidepressant for somatic symptom disorder?

    Citalopram enhances serotonin activity through selective reuptake inhibition at the neuronal membrane. It may be useful in the treatment of somatic symptoms associated with generalized anxiety disorder.

    Can somatic symptom disorder be cured?

    Somatic symptom and related disorder treatment Although there is no known cure for somatoform disorders, they can be managed. Treatment focuses on helping the person who has the disorder to live as much of a normal life as possible. Even with treatment, he or she may still have some pain or other symptoms.