Which pain description with the nurse expect the client to report when describing pain associated with a suspected duodenal peptic ulcer?

This is a quiz that contains NCLEX review questions for peptic ulcer disease. As a nurse providing care to a patient with peptic ulcer disease, it is important to know the signs and symptoms, pathophysiology, medications, nursing management, diet education, and complications.

In the previous NCLEX review series, I explained about other GI disorders you may be asked about on the NCLEX exam, so be sure to check out those reviews and quizzes as well.

Peptic Ulcer Disease NCLEX Practice Questions

This quiz will test you on peptic ulcer disease in preparation for the NCLEX exam.

• 1. In the stomach lining, the parietal cells release _________ and the chief cells release __________ which both play a role in peptic ulcer disease.*
  • A. pepsin, hydrochloric acid
  • B. pepsinogen, pepsin
  • C. pepsinogen, gastric acid
  • D. hydrochloric acid, and pepsinogen

• 2. A patient has developed a duodenal ulcer. As the nurse, you know that which of the following plays a role in peptic ulcer formation. Select ALL that apply:*
  • A. Spicy foods
  • B. Helicobacter pylori
  • C. NSAIDs
  • D. Milk
  • E. Zollinger-Ellison Syndrome

• 3. You're educating a group of patients at an outpatient clinic about peptic ulcer formation. Which statement is correct about how peptic ulcers form?*
  • A. "An increase in gastric acid is the sole cause of peptic ulcer formation."
  • B. "Peptic ulcers can form when acid penetrates unprotected stomach mucosa. This causes histamine to be released which signals to the parietal cells to release more hydrochloric acid which erodes the stomach lining further."
  • C. "Peptic ulcers form when acid penetrates unprotected stomach mucosa. This causes pepsin to be released which signals to the parietal cells to release more pepsinogen which erodes the stomach lining further."
  • D. "The release of prostaglandins cause the stomach lining to breakdown which allows ulcers to form."

• 4. Your patient is diagnosed with peptic ulcer disease due to h.pylori. This bacterium has a unique shape which allows it to penetrate the stomach mucosa. You know this bacterium is:*
  • A. Rod shaped
  • B. Spherical shaped
  • C. Spiral shaped
  • D. Filamentous shaped

• 5. Helicobacter pylori can live in the stomach's acidic conditions because it secretes ___________ which neutralizes the acid.*
  • A. ammonia
  • B. urease
  • C. carbon dioxide
  • D. bicarbonate

• 6. The physician orders a patient with a duodenal ulcer to take a UREA breath test. Which lab value will the test measure to determine if h. pylori is present?*
  • A. Ammonia
  • B. Urea
  • C. Hydrochloric acid
  • D. Carbon dioxide

• 7. A patient arrives to the clinic for evaluation of epigastric pain. The patient describes the pain to be relieved by food intake. In addition, the patient reports awaking in the middle of the night with a gnawing pain in the stomach. Based on the patient's description this appears to be what type of peptic ulcer?*
  • A. Duodenal
  • B. Gastric
  • C. Esophageal
  • D. Refractory

• 8. A patient with chronic peptic ulcer disease underwent a gastric resection 1 month ago and is reporting nausea, bloating, and diarrhea 30 minutes after eating. What condition is this patient most likely experiencing?*
  • A. Gastroparesis
  • B. Fascia dehiscence
  • C. Dumping Syndrome
  • D. Somogyi effect

• 9. Thinking back to the patient in question 8, select ALL the correct statements on how to educate this patient about decreasing their symptoms:*
  • A. "It is best to eat 3 large meals a day rather than small frequent meals."
  • B. "After eating a meal lie down for 30 minutes."
  • C. "Eat a diet high in protein, fiber, and low in carbs."
  • D. "Be sure to drink at least 16 oz. of milk with meals."

• 10. A patient is recovering from discomfort from a peptic ulcer. The doctor has ordered to advance the patient’s diet to solid foods. The patient's lunch tray arrives. Which food should the patient avoid eating?*
  • A. Orange
  • B. Milk
  • C. White rice
  • D. Banana

• 11. Which statement is INCORRECT about Histamine-receptor blockers?*
  • A. "H2 blockers block histamine which causes the chief cells to decrease the secretion of hydrochloric acid."
  • B. "Ranitidine and Famotidine are two types of histamine-receptor blocker medications."
  • C. "Antacids and H2 blockers should not be given together."
  • D. All the statements are CORRECT.

• 12. You are providing discharge teaching to a patient taking Sucralfate (Carafate). Which statement by the patient demonstrates they understand how to take this medication?*
  • A. "I will take this medication at the same time I take Ranitidine."
  • B. "I will always take this medication on an empty stomach."
  • C. "It is best to take this medication with antacids."
  • D. "I will take this medication once a week."

• 13. Select all the medications a physician may order to treat a H. Pylori infection that is causing a peptic ulcer?*
  • A. Proton-Pump Inhibitors
  • B. Antacids
  • C. Anticholinergics
  • D. 5-Aminosalicylates
  • E. Antibiotics
  • F. H2 Blockers
  • G. Bismuth Subsalicylates

• 14. A physician prescribes a Proton-Pump Inhibitor to a patient with a gastric ulcer. Which medication is considered a PPI?*
  • A. Pantoprazole
  • B. Famotidine
  • C. Magnesium Hydroxide
  • D. Metronidazole

• 15. A patient with a peptic ulcer is suddenly vomiting dark coffee ground emesis. On assessment of the abdomen you find bloating and an epigastric mass in the abdomen. Which complication may this patient be experiencing?*
  • A. Obstruction of pylorus
  • B. Upper gastrointestinal bleeding
  • C. Perforation
  • D. Peritonitis

(NOTE: When you hit submit, it will refresh this same page. Scroll down to see your results.)

Peptic Ulcer Disease NCLEX Questions

1. In the stomach lining, the parietal cells release _________ and the chief cells release __________ which both play a role in peptic ulcer disease.

A. pepsin, hydrochloric acid

B. pepsinogen, pepsin

C. pepsinogen, gastric acid

D. hydrochloric acid, and pepsinogen

2. A patient has developed a duodenal ulcer. As the nurse, you know that which of the following plays a role in peptic ulcer formation. Select ALL that apply:

A. Spicy foods

B. Helicobacter pylori

C. NSAIDs

D. Milk

E. Zollinger-Ellison Syndrome

3. You’re educating a group of patients at an outpatient clinic about peptic ulcer formation. Which statement is correct about how peptic ulcers form?

A. “An increase in gastric acid is the sole cause of peptic ulcer formation.”

B. “Peptic ulcers can form when acid penetrates unprotected stomach mucosa. This causes histamine to be released which signals to the parietal cells to release more hydrochloric acid which erodes the stomach lining further.”

C. “Peptic ulcers form when acid penetrates unprotected stomach mucosa. This causes pepsin to be released which signals to the parietal cells to release more pepsinogen which erodes the stomach lining further.”

D. “The release of prostaglandins cause the stomach lining to breakdown which allows ulcers to form.”

4. Your patient is diagnosed with peptic ulcer disease due to h.pylori. This bacterium has a unique shape which allows it to penetrate the stomach mucosa. You know this bacterium is:

A. Rod shaped

B. Spherical shaped

C. Spiral shaped

D. Filamentous shaped

5. Helicobacter pylori can live in the stomach’s acidic conditions because it secretes ___________  which neutralizes the acid.

A. ammonia

B. urease

C. carbon dioxide

D. bicarbonate

6. The physician orders a patient with a duodenal ulcer to take a UREA breath test. Which lab value will the test measure to determine if h. pylori is present?

A. Ammonia

B. Urea

C. Hydrochloric acid

D. Carbon dioxide

7. A patient arrives to the clinic for evaluation of epigastric pain. The patient describes the pain to be relieved by food intake. In addition, the patient reports awaking in the middle of the night with a gnawing pain in the stomach. Based on the patient’s description this appears to be what type of peptic ulcer?

A. Duodenal

B. Gastric

C. Esophageal

D. Refractory

8. A patient with chronic peptic ulcer disease underwent a gastric resection 1 month ago and is reporting nausea, bloating, and diarrhea 30 minutes after eating. What condition is this patient most likely experiencing?

A. Gastroparesis

B. Fascia dehiscence

C. Dumping Syndrome

D. Somogyi effect

9. Thinking back to the patient in question 8, select ALL the correct statements on how to educate this patient about decreasing their symptoms:

A. “It is best to eat 3 large meals a day rather than small frequent meals.”

B. “After eating a meal lie down for 30 minutes.”

C. “Eat a diet high in protein, fiber, and low in carbs.”

D. “Be sure to drink at least 16 oz. of milk with meals.”

10. A patient is recovering from discomfort from a peptic ulcer. The doctor has ordered to advance the patient’s diet to solid foods. The patient’s lunch tray arrives. Which food should the patient avoid eating?

A. Orange

B. Milk

C. White rice

D. Banana

11. Which statement is INCORRECT about Histamine-receptor blockers?

A. “H2 blockers block histamine which causes the chief cells to decrease the secretion of hydrochloric acid.”

B. “Ranitidine and Famotidine are two types of histamine-receptor blocker medications.”

C. “Antacids and H2 blockers should not be given together.”

D. All the statements are CORRECT.

12. You are providing discharge teaching to a patient taking Sucralfate (Carafate). Which statement by the patient demonstrates they understand how to take this medication?

A. “I will take this medication at the same time I take Ranitidine.”

B. “I will always take this medication on an empty stomach.”

C. “It is best to take this medication with antacids.”

D. “I will take this medication once a week.”

13. Select all the medications a physician may order to treat a H. Pylori infection that is causing a peptic ulcer?

A. Proton-Pump Inhibitors

B. Antacids

C. Anticholinergics

D. 5-Aminosalicylates

E. Antibiotics

F. H2 Blockers

G. Bismuth Subsalicylates

14. A physician prescribes a Proton-Pump Inhibitor to a patient with a gastric ulcer. Which medication is considered a PPI?

A. Pantoprazole

B. Famotidine

C. Magnesium Hydroxide

D. Metronidazole

15. A patient with a peptic ulcer is suddenly vomiting dark coffee ground emesis. On assessment of the abdomen you find bloating and an epigastric mass in the abdomen. Which complication may this patient be experiencing?

A. Obstruction of pylorus

B. Upper gastrointestinal bleeding

C. Perforation

D. Peritonitis

Answer Key:

1. D
2. B, C, E
3. B
4. C
5. B
6. D
7. A
8. C
9. B, C
10. A
11. A
12. B
13. A, E, F, G
14. A
15. B

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