Long-term alcohol abuse may lead to some types of cancer

Long-term alcohol abuse may lead to some types of cancer

Drinking too much – on a single occasion or over time – can take a serious toll on your health.  Here’s how alcohol can affect your body:

Brain:
Alcohol interferes with the brain’s communication pathways, and can affect the way the brain looks and works. These disruptions can change mood and behavior, and make it harder to think clearly and move with coordination.  

Heart:
Drinking a lot over a long time or too much on a single occasion can damage the heart, causing problems including:

  • Cardiomyopathy – Stretching and drooping of heart muscle
  • Arrhythmias – Irregular heart beat
  • Stroke
  • High blood pressure  

Liver:
Heavy drinking takes a toll on the liver, and can lead to a variety of problems and liver inflammations including:

  • Steatosis, or fatty liver
  • Alcoholic hepatitis
  • Fibrosis
  • Cirrhosis

Pancreas:
Alcohol causes the pancreas to produce toxic substances that can eventually lead to pancreatitis, a dangerous inflammation and swelling of the blood vessels in the pancreas that prevents proper digestion. 

Cancer:
According to the National Cancer Institute: "There is a strong scientific consensus that alcohol drinking can cause several types of cancer. In its Report on Carcinogens, the National Toxicology Program of the US Department of Health and Human Services lists consumption of alcoholic beverages as a known human carcinogen.

"The evidence indicates that the more alcohol a person drinks–particularly the more alcohol a person drinks regularly over time–the higher his or her risk of developing an alcohol-associated cancer. Even those who have no more than one drink per day and people who binge drink (those who consume 4 or more drinks for women and 5 or more drinks for men in one sitting) have a modestly increased risk of some cancers. Based on data from 2009, an estimated 3.5% of cancer deaths in the United States (about 19,500 deaths were alcohol related."

Clear patterns have emerged between alcohol consumption and increased risks of certain types of cancer:

  • Head and neck cancer, including oral cavity, pharynx, and larynx cancers.
  • Esophageal cancer, particularly esophageal squamous cell carcinoma. In addition, people who inherit a deficiency in an enzyme that metabolizes alcohol have been found to have substantially increased risks of esophageal squamous cell carcinoma if they consume alcohol.
  • Liver cancer.
  • Breast cancer: Studies have consistently found an increased risk of breast cancer in women with increasing alcohol intake. Women who consume about 1 drink per day have a 5 to 9 percent higher chance of developing breast cancer than women who do not drink at all.
  • Colorectal cancer.

For more information about alcohol and cancer, please visit the National Cancer Institute's webpage "Alcohol and Cancer Risk" (last accessed October 21, 2021).

Immune System:
Drinking too much can weaken your immune system, making your body a much easier target for disease.  Chronic drinkers are more liable to contract diseases like pneumonia and tuberculosis than people who do not drink too much.  Drinking a lot on a single occasion slows your body’s ability to ward off infections – even up to 24 hours after getting drunk.

For more information about alcohol's effects on the body, please visit the Interactive Body feature on NIAAA's College Drinking Prevention website.

Health Risks of Chronic Heavy Drinking

Medically Reviewed by Jennifer Robinson, MD on March 16, 2021

If you have a little too much alcohol once in a while, it probably won’t do lasting damage if you’re otherwise healthy. But it’s a different story if you regularly drink heavily.

For most men, that’s defined as more than 4 drinks a day, or 14 or 15 in a week. For women, heavy drinking is more than 3 drinks in a day, or 7 or 8 per week.

Too much alcohol can harm you physically and mentally in lots of ways.

Liver Damage

Alcohol is a toxin, and it’s your liver’s job to flush it out of your body. But your liver may not be able to keep up if you drink too much too fast. Alcohol can kill liver cells, and lead to scarring called cirrhosis. Long-term heavy use of alcohol also may give you alcoholic fatty liver disease, a sign that your liver doesn’t work as well as it should.

Heart Disease

You may know about the dangers of blood clots and high levels of fats and cholesterol in your body. Alcohol makes both things more likely. Studies of heavy drinkers also show that they are more likely to have trouble pumping blood to their heart and may have a higher chance of dying from heart disease.

Brain and Nervous System Problems

Alcohol affects the brain’s communication pathways. This makes it harder for you to think and speak clearly, remember things, make decisions, and move your body. Heavy drinking also can cause mental health issues like depression and dementia. You may get painful nerve damage that may linger long after you sober up.

Anemia

This is when your body doesn’t make enough healthy red blood cells to move oxygen around. That may give you ulcers, inflammation, and other problems. Too much booze may also make you more likely to skip meals, which can short-change your body of iron.

Cancer

There is a clear link between heavy alcohol use and many types of cancers. Alcohol can damage the cells in your mouth, throat, voice box, and esophagus. It can lead to cancers in your liver, breast, and intestines. Alcohol can help cancer-causing chemicals in tobacco and other sources enter your cells more easily.

Seizures

Long-term alcohol abuse may raise your chances for epilepsy. And alcohol withdrawal after heavy drinking can cause seizures.

Gout

This form of arthritis results from painful buildup of uric acid in the joints. You can get gout from eating too much food high in chemicals called purines, which include red meat, shellfish, and alcohol -- especially beer and liquor.

Infections

Heavy drinking can hamper your immune cells from fighting off viruses and bacteria. It also can harm your liver, which plays an important role in your immune system by making antibacterial proteins.

Digestive Problems

Booze is caustic. It can inflame the stomach lining, causing heartburn and nausea. Over time, this can give you ulcers and chronic inflammation in your stomach, esophagus, and gut. It can also make it harder for your intestines to digest important nutrients like B12 and thiamine. Alcohol can also cause a buildup of digestive enzymes in the pancreas, leading to a condition called pancreatitis, or an inflamed pancreas. This can affect how much insulin you make, putting you at higher risk for diabetes.

Sleep

Knocking back a lot of drinks may knock you out at night. But once the sedative effect wears off, it can disrupt or lower the quality of your sleep. Binge drinking too often can make it harder to fall asleep and stay asleep. It can also increase snoring and sleep apnea, making it hard to get a good night’s rest.

How to Get Help

If you think you might have a problem with alcohol, get help. Talk to your doctor, therapist, or an addiction specialist. Find online support groups. Some people manage to kick the habit on their own. But if you feel you need extra help, you may want to check out your local branch of Alcoholics Anonymous. Learn more about outpatient alcohol treatment.

Can long term alcohol abuse cause cancer?

All alcoholic drinks, including red and white wine, beer, and liquor, are linked with cancer. The more you drink, the higher your cancer risk.
Cancers of the mouth, throat, voice box, and esophagus: Alcohol use clearly raises the risk of these cancers..
Mouth..
Throat (pharynx).
Voice box (larynx).
Esophagus..
Liver..
Colon and rectum..
Breast..

What are the 7 types of cancer caused by alcohol?

A New Zealand study has found “strong evidence” that alcohol causes seven types of cancer — oropharynx, larynx, esophagus, liver, colon, rectum and breast cancer — and “probably others” such as pancreas, prostate and skin cancer.

What cancers can alcohol lead to?

Alcohol is a known carcinogen. This means that alcohol causes cancer. There is strong evidence that drinking alcohol increases people's risk of cancers of the female breast, liver, mouth, throat (pharynx and larynx), oesophagus and bowel. Heavy drinking may also increase people's risk of stomach cancer.